{"id":5676,"date":"2025-05-20T09:13:45","date_gmt":"2025-05-20T09:13:45","guid":{"rendered":"https:\/\/optimumdermatology.com\/b-dermatiko-lemfoma-blastikoy-kentroy\/"},"modified":"2025-10-16T14:09:19","modified_gmt":"2025-10-16T14:09:19","slug":"b-dermatiko-lemfoma-blastikoy-kentroy","status":"publish","type":"page","link":"https:\/\/optimumdermatology.com\/en\/b-dermatiko-lemfoma-blastikoy-kentroy\/","title":{"rendered":"Primary Cutaneous Follicle Center Lymphoma (PCFCL)"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"5676\" class=\"elementor elementor-5676 elementor-3313\" data-elementor-post-type=\"page\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-e968d4d elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"e968d4d\" data-element_type=\"section\" data-settings=\"{&quot;wdt_bg_image&quot;:{&quot;url&quot;:&quot;&quot;,&quot;id&quot;:&quot;&quot;,&quot;size&quot;:&quot;&quot;},&quot;wdt_bg_image_widescreen&quot;:{&quot;url&quot;:&quot;&quot;,&quot;id&quot;:&quot;&quot;,&quot;size&quot;:&quot;&quot;},&quot;wdt_bg_image_laptop&quot;:{&quot;url&quot;:&quot;&quot;,&quot;id&quot;:&quot;&quot;,&quot;size&quot;:&quot;&quot;},&quot;wdt_bg_image_tablet_extra&quot;:{&quot;url&quot;:&quot;&quot;,&quot;id&quot;:&quot;&quot;,&quot;size&quot;:&quot;&quot;},&quot;wdt_bg_image_tablet&quot;:{&quot;url&quot;:&quot;&quot;,&quot;id&quot;:&quot;&quot;,&quot;size&quot;:&quot;&quot;},&quot;wdt_bg_image_mobile_extra&quot;:{&quot;url&quot;:&quot;&quot;,&quot;id&quot;:&quot;&quot;,&quot;size&quot;:&quot;&quot;},&quot;wdt_bg_image_mobile&quot;:{&quot;url&quot;:&quot;&quot;,&quot;id&quot;:&quot;&quot;,&quot;size&quot;:&quot;&quot;},&quot;wdt_bg_position&quot;:&quot;center center&quot;,&quot;wdt_animation_effect&quot;:&quot;none&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-db31503\" data-id=\"db31503\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-fc57a00 elementor-widget-divider--view-line_text elementor-widget-divider--element-align-center elementor-widget elementor-widget-divider\" data-id=\"fc57a00\" data-element_type=\"widget\" data-settings=\"{&quot;wdt_animation_effect&quot;:&quot;none&quot;}\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t\t<h1 class=\"elementor-divider__text elementor-divider__element\">\n\t\t\t\tPrimary Cutaneous Follicle Center Lymphoma (PCFCL)\t\t\t\t<\/h1>\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-5703a92 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"5703a92\" data-element_type=\"section\" data-settings=\"{&quot;wdt_bg_image&quot;:{&quot;url&quot;:&quot;&quot;,&quot;id&quot;:&quot;&quot;,&quot;size&quot;:&quot;&quot;},&quot;wdt_bg_image_widescreen&quot;:{&quot;url&quot;:&quot;&quot;,&quot;id&quot;:&quot;&quot;,&quot;size&quot;:&quot;&quot;},&quot;wdt_bg_image_laptop&quot;:{&quot;url&quot;:&quot;&quot;,&quot;id&quot;:&quot;&quot;,&quot;size&quot;:&quot;&quot;},&quot;wdt_bg_image_tablet_extra&quot;:{&quot;url&quot;:&quot;&quot;,&quot;id&quot;:&quot;&quot;,&quot;size&quot;:&quot;&quot;},&quot;wdt_bg_image_tablet&quot;:{&quot;url&quot;:&quot;&quot;,&quot;id&quot;:&quot;&quot;,&quot;size&quot;:&quot;&quot;},&quot;wdt_bg_image_mobile_extra&quot;:{&quot;url&quot;:&quot;&quot;,&quot;id&quot;:&quot;&quot;,&quot;size&quot;:&quot;&quot;},&quot;wdt_bg_image_mobile&quot;:{&quot;url&quot;:&quot;&quot;,&quot;id&quot;:&quot;&quot;,&quot;size&quot;:&quot;&quot;},&quot;wdt_bg_position&quot;:&quot;center center&quot;,&quot;wdt_animation_effect&quot;:&quot;none&quot;}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-e921780\" data-id=\"e921780\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-ce3698d elementor-widget elementor-widget-heading\" data-id=\"ce3698d\" data-element_type=\"widget\" data-settings=\"{&quot;wdt_animation_effect&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Definition<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-934c8e4 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"934c8e4\" data-element_type=\"widget\" data-settings=\"{&quot;wdt_animation_effect&quot;:&quot;none&quot;}\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-91f4719 elementor-widget elementor-widget-text-editor\" data-id=\"91f4719\" data-element_type=\"widget\" data-settings=\"{&quot;wdt_animation_effect&quot;:&quot;none&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span lang=\"EN-US\" style=\"color: black;\">Primary Cutaneous Follicle Center Lymphoma (PCFCL) is a rare form of cutaneous lymphoma originating from follicle center B-cells\u2014a specific type of lymphocyte found in lymphoid tissue. It is an indolent, slow-growing malignancy with a favorable prognosis (10-year survival rate &gt;90%).<br \/>\u2022 Early diagnosis<br \/>\u2022 Personalized treatment approaches for each case<br \/>\u2022 Therapeutic plan optimization based on disease severity and spread<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6e043a8 elementor-widget elementor-widget-heading\" data-id=\"6e043a8\" data-element_type=\"widget\" data-settings=\"{&quot;wdt_animation_effect&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Morphology<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5a0303f elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"5a0303f\" data-element_type=\"widget\" data-settings=\"{&quot;wdt_animation_effect&quot;:&quot;none&quot;}\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8066717 elementor-widget elementor-widget-text-editor\" data-id=\"8066717\" data-element_type=\"widget\" data-settings=\"{&quot;wdt_animation_effect&quot;:&quot;none&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Lesions may appear as solitary or grouped plaques or tumors, typically located on the scalp, forehead, trunk, and\u2014rarely\u2014on the lower limbs.<br \/>Trunk lesions are often surrounded by erythematous infiltrated plaques, which may precede the development of the tumor by months or even years.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-947bcea elementor-widget elementor-widget-heading\" data-id=\"947bcea\" data-element_type=\"widget\" data-settings=\"{&quot;wdt_animation_effect&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Etiology<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-aa421e7 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"aa421e7\" data-element_type=\"widget\" data-settings=\"{&quot;wdt_animation_effect&quot;:&quot;none&quot;}\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-9d5715f elementor-widget elementor-widget-text-editor\" data-id=\"9d5715f\" data-element_type=\"widget\" data-settings=\"{&quot;wdt_animation_effect&quot;:&quot;none&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>The exact cause of Primary Cutaneous Follicle Center Lymphoma (PCFCL) is not fully understood.<br \/>However, it appears to be associated with heightened immune system activity and may result from genetic predisposition or acquired abnormalities in the genetic material of B-lymphocytes.<br \/>Some cases have been linked to chronic inflammation or autoimmune diseases. Infections or prior treatments that impact immune responses have also been implicated.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3de99a3 elementor-widget elementor-widget-heading\" data-id=\"3de99a3\" data-element_type=\"widget\" data-settings=\"{&quot;wdt_animation_effect&quot;:&quot;none&quot;}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Diagnosis &amp; Treatment<\/h4>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b8ca22c elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"b8ca22c\" data-element_type=\"widget\" data-settings=\"{&quot;wdt_animation_effect&quot;:&quot;none&quot;}\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-78761c5 elementor-widget elementor-widget-text-editor\" data-id=\"78761c5\" data-element_type=\"widget\" data-settings=\"{&quot;wdt_animation_effect&quot;:&quot;none&quot;}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p>Diagnosis is typically established through skin biopsy and histopathological evaluation.<br \/>Treatment depends on the extent and severity of the lymphoma. Common therapeutic strategies include chemotherapy, radiotherapy, and, in some cases, biological agents such as rituximab. Surgical excision is considered when the lesion is localized.<br \/>While the prognosis is generally excellent in early-stage disease, the risk of recurrence increases in more advanced cases.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Primary Cutaneous Follicle Center Lymphoma (PCFCL) Definition Primary Cutaneous Follicle Center Lymphoma (PCFCL) is a rare form of cutaneous lymphoma originating from follicle center B-cells\u2014a specific type of lymphocyte found in lymphoid tissue. It is an indolent, slow-growing malignancy with a favorable prognosis (10-year survival rate &gt;90%).\u2022 Early diagnosis\u2022 Personalized treatment approaches for each case\u2022 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"tpl-side-nav.php","meta":{"footnotes":""},"class_list":["post-5676","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/optimumdermatology.com\/en\/wp-json\/wp\/v2\/pages\/5676","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/optimumdermatology.com\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/optimumdermatology.com\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/optimumdermatology.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/optimumdermatology.com\/en\/wp-json\/wp\/v2\/comments?post=5676"}],"version-history":[{"count":4,"href":"https:\/\/optimumdermatology.com\/en\/wp-json\/wp\/v2\/pages\/5676\/revisions"}],"predecessor-version":[{"id":5680,"href":"https:\/\/optimumdermatology.com\/en\/wp-json\/wp\/v2\/pages\/5676\/revisions\/5680"}],"wp:attachment":[{"href":"https:\/\/optimumdermatology.com\/en\/wp-json\/wp\/v2\/media?parent=5676"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}